Hotel in Sikeston with a fitness center and a 24-hour front desk This hotel features an indoor pool, a fitness center, and a business center. Free WiFi in public areas and free self parking are also provided. Other amenities include laundry facilities, a 24-hour front desk, and a front-desk safe. Comfort Inn & Suites Sikeston I-55 offers 64 air-conditioned accommodations with coffee/tea makers. Guests can surf the web using the complimentary wireless Internet access. Bathrooms include bathtubs or showers. Business-friendly amenities include desks and phones. Recreational amenities at the hotel include an indoor pool and a fitness center.